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Early clinical trials of ARD-101 have shown promise in significantly mitigating hunger and decreased appetite in patients with Prader-Willi Syndrome, a condition characterized by chronic hunger and obesity

Each increase typically comes with a brief adjustment period followed by enhanced effects

Studies show sustained weight loss, improved metabolic markers, and cardiovascular benefits

Update to a position statement of the American Diabetes As- sociation and the European Association for the Study of Diabetes

Renal elimination of unchanged orforglipron is minimal, suggesting that dose adjustment in patients with renal impairment may not be necessary